Optimizing Responsive Websites for Users and Search Engines
tl;dr:My Intersect presentation on mobile-first, responsive design methods and iterative component-based design.
I gave this presentation at Intersect 3.0 in Salt Lake City. The deck outlines some of the methods you can optimize responsive design for both users and search engines.
If you have any questions or feedback, feel free to ping me via Twitter @robkellas.